Publications by authors named "M V Cooley"
Purpose: The self-assessment is a component of the National Training and Development Curriculum (NTDC) used by resource (i.e. foster, adoptive, and kinship) parents to understand strengths and areas of potential growth associated with successful parenting.
View Article and Find Full Text PDFThe 18 Workshop on Recent Issues in Bioanalysis (18 WRIB) took place in San Antonio, TX, USA on May 6-10, 2024. Over 1100 professionals representing pharma/biotech companies, CROs, and multiple regulatory agencies convened to actively discuss the most current topics of interest in bioanalysis. The 18 WRIB included 3 Main Workshops and 7 Specialized Workshops that together spanned 1 week to allow an exhaustive and thorough coverage of all major issues in bioanalysis of biomarkers, immunogenicity, gene therapy, cell therapy and vaccines.
View Article and Find Full Text PDFThe incidence of obesity has dramatically increased worldwide. Obesity has been shown to exacerbate the progression of periodontal disease. Studies suggest a sex difference in periodontitis, whereby males are more sensitive to periodontal inflammation compared to females.
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- This study examined how two levels of low-intensity vibration training (0.6 g and 1.0 g) affected muscle and bone recovery in mice after a muscle injury known as volumetric muscle loss (VML).
- Mice were divided into groups receiving either no treatment or varying levels of vibration training for 15 minutes a day over 8 weeks post-injury.
- Results showed that bone structure improved with vibration training, particularly at the 1.0 g level, while muscle function showed less significant enhancement, suggesting that vibration training may be more beneficial for bone recovery than for muscle after VML.
Article Synopsis
- The study investigates challenges in delivering nanoparticle-based drugs to tumors, focusing on the inconsistent success of the enhanced permeability and retention (EPR) effect.
- It introduces a technique using multiparametric dynamic contrast-enhanced ultrasound (CEUS) with nanoscale contrast agents to noninvasively analyze tumor microenvironment features and predict the distribution and effectiveness of doxorubicin-laden liposomes.
- Results indicate that CEUS parameters, like area under the curve and decorrelation time, can accurately differentiate between tumors with varying vascular permeability, potentially serving as biomarkers for treatment responsiveness to nanoparticle therapies.