Perioperative testosterone supplementation improves outcomes of orthopedic surgeries: A Systematic review of heterogeneous studies.

Purpose: The purpose of this study is to assess the effect of perioperative testosterone supplementation on orthopedic surgical outcomes.

Methods: Three online databases were searched from database inception until September 2024. Three reviewers independently screened all titles, abstracts, and full-texts of articles investigating perioperative testosterone use in orthopedic surgery.

Anterior Cruciate Ligament Reconstruction with Internal Brace Augmentation Results in Fewer Reruptures Compared to Reconstruction without Augmentation.

 To compare the clinical outcomes of anterior cruciate ligament (ACL) reconstruction using autografts with and without internal brace augmentation.  Data from patients who underwent ACL reconstruction with hamstring and quadriceps tendon autografts, with a minimum follow-up of one year, with or without internal brace augmentation were collected prospectively analyzed retrospectively. The Lysholm and Tegner functional scores were collected before and after surgery, as well as data on postoperative complications.

Moral conviction interacts with metacognitive ability in modulating neural activity during sociopolitical decision-making.

The extent to which a belief is rooted in one's sense of morality has significant societal implications. While moral conviction can inspire positive collective action, it can also prompt dogmatism, intolerance, and societal divisions. Research in social psychology has documented the functional characteristics of moral conviction and shows that poor metacognition exacerbates its negative outcomes.

Differences in Emotional Awareness Moderate Cytokine-Symptom Associations Among Breast Cancer Survivors.

Cancer survivors have elevated levels of proinflammatory cytokines, which could be associated with cancer-related symptoms. Given that proinflammatory cytokines heighten negative affect by directly affecting the brain, we explored these direct associations and whether differences in levels of emotional awareness moderate the associations between proinflammatory cytokines and cancer-related symptoms. This cross-sectional, secondary analysis of baseline data was collected from 162 female breast cancer survivors (aged 36-70 years), who were enrolled 6 ± 4 months after completing cancer treatment.

Heterogeneous depressive symptom trajectories among women with type 2 diabetes: findings from the Women's Interagency HIV Study.

Background: Depression affects 33% of women with type 2 diabetes (T2D) and leads to increased risks of premature mortality. Fluctuation and variation of depressive presentations can hinder clinical identification.

Purpose: We aimed to identify and examine subgroups characterized by distinct depressive symptom trajectories among women with T2D.