Publications by authors named "M V Chakravarthy"
Measuring single-cell genomic profiles at different timepoints enables our understanding of cell development. This understanding is more comprehensive when we perform an integrative analysis of multiple measurements (or modalities) across various developmental stages. However, obtaining such measurements from the same set of single cells is resource-intensive, restricting our ability to study them integratively.
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- - The patient, a cardiac transplant recipient, experienced symptoms of right eye pain and blurry vision.
- - Upon investigation, she was diagnosed with intracardiac aspergilloma that affected her pericardium, alongside complications like endogenous endophthalmitis and an acute heart attack.
- - Treatment included a mechanical debulking procedure using the Angiovac system to address the aspergilloma.
Article Synopsis
- The growth of publicly available single-cell datasets has greatly improved our understanding of biology, but it raises significant privacy issues.
- Recent studies on data sharing have mainly focused on bulk gene expression data due to noise and a lack of large single-cell datasets.
- Our research reveals that individuals in single-cell datasets are at risk of linking attacks that expose sensitive information, and we propose a method for predicting genotypes that operates independently of eQTLs, allowing for the discovery of private information across different studies.
Simultaneous surgical management of malignancy and coronary heart disease.
Indian J Thorac Cardiovasc Surg
July 2024
Coronary heart disease and cancer are the most common causes of mortality across the globe. It has been a dilemma for the surgical team to decide which surgical procedure should be done first when a patient needs surgery for both. This is a single-center retrospective observational study.
View Article and Find Full Text PDFBackground: Atypical myxoma has been reported in various locations in the heart, however, myxoma involving the pulmonary valve is rare. Here we present a case of pulmonic valve myxoma which was resected via a percutaneous approach.
Case Report: A 66-year-old female with known metastatic adenocarcinoma of the lung, and chronic obstructive pulmonary disease presented with acute onset shortness of breath for two days.