Publications by authors named "M V Arisov"

Article Synopsis
  • - The study assesses giardiasis, a common protozoal disease in dogs and cats, focusing on its prevalence and age susceptibility in domestic pets.
  • - It involved microscopic examination of fecal samples from over 4000 dogs and cats, noting stool characteristics alongside age data.
  • - Findings revealed higher infection rates in younger animals (under 12 months) and highlighted soft or mushy stools and strong odors as common symptoms, emphasizing the need for ongoing health checks in seemingly healthy pets.
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This study was aimed to determine the prevalence of , spp., and spp., which occur and are potentially zoonotic to humans in domestic dogs and cats in Moscow (Russia).

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A supramolecular complex of fenbendazole (SFBZ) with polyvinylpyrrolidone (PVP) was created by mechanochemical processing to increase its anthelmintic efficacy and to reduce the dose of applied drugs. The aim of our research was to study the pharmacokinetic profile and tissue residue depletion of fenbendazole (FBZ) and its metabolites: sulfoxide and sulfone in sheep after SFBZ treatment by high-performance liquid chromatography with tandem mass spectrometric detection and to evaluate its efficacy against gastrointestinal strongylatosis of sheep in field trials. The results revealed that FBZ and its metabolites were detected in blood serum in 2 h after SFBZ administration and in 4-6 h after the administration of the basic - FBZ.

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The World Health Organization declared the pandemic situation caused by SARSCoV- 2 (Severe Acute Respiratory Syndrome Coronavirus-2) in March 2020, but the detailed pathophysiological mechanisms of Coronavirus disease 2019 (COVID-19) are not yet completely understood. Therefore, to date, few therapeutic options are available for patients with mildmoderate or serious disease. In addition to systemic and respiratory symptoms, several reports have documented various neurological symptoms and impairments of mental health.

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Background: A supramolecular complex of praziquantel (PZQ) with disodium salt of glycyrrhizic acid (NaGA) was obtained by mechanochemical technology to increase solubility, absorption rate and hence bioavailability of the drug and reduction its therapeutic doses. The aim of our study was evaluation of anthelmintic efficacy of supramolecular complex of PZQ.

Methods: Different samples of PZQ with NaGA were obtained by mechanochemical processing and examined for some physico-chemical properties.

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