Publications by authors named "M V Aleshina"
Western Siberia is the region with little information on the prevalence of hepatitis C virus (HCV) infection, genotypic diversity of HCV isolates and risk factors. A molecular epidemiological survey was conducted to clarify these issues. Four groups of volunteers were included in a cross-sectional study (n = 500 in each group): health care workers; daycare patients from a hospital for drug users, daycare patients from an AIDS prevention and control center; and persons admitted to a local general practice clinic for any reason (outpatients).
View Article and Find Full Text PDFArticle Synopsis
- A study in Novosibirsk involving 2,000 residents examined the prevalence, genotypes, and risk factors for hepatitis C (HCV), finding anti-HCV IgG rates from 4.6% in medical staff to 48% in drug clinic patients.
- The HCV RNA detection rate was high (79.3% to 86.3%) with genotypic analysis revealing 50.3% of cases as genotype 1b, and showing that drug use significantly increased HCV risk.
- Among various groups, risks were notably higher for unemployed individuals, alcohol abusers, and those with multiple sexual partners, with genotype 3 more strongly associated with intravenous drug use, especially among younger people