A novel strategy based on histological protein profiling in-silico for identifying potential biomarkers in urinary bladder cancer.

Objective: To screen a publicly available immunohistochemistry (IHC) based web-atlas, to identify key proteins in bladder cancer that might serve as potential biomarkers.

Materials And Methods: The first version of the Human Protein Atlas (HPA 1.0), with 660 proteins, was visually examined to identify proteins with a variable staining pattern among the 12 tissue samples representing bladder cancer.