Publications by authors named "M Uhrich"

Background/aims: Age-related cognitive decline is a pervasive problem in our aging population. To date, no pharmacological treatments to halt or reverse cognitive decline are available. Behavioral interventions, such as physical exercise and Mindfulness-Based Stress Reduction, may reduce or reverse cognitive decline, but rigorously designed randomized controlled trials are needed to test the efficacy of such interventions.

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The aim of this study was to explore the relationship of aerobic fitness with the elementary school environment and student characteristics among 4th and 5th grade children attending urban public schools in St. Louis, MO, USA. This cross-sectional study was conducted during 2012-2015 and included 2381 children (mean age 10.

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Article Synopsis
  • The CALERIE study was the first randomized trial to investigate the effects of calorie restriction (CR) on health in nonobese humans, focusing on aerobic capacity (V˙O2max) and muscle strength.
  • In the study, 218 participants were divided into a CR group (25% reduction in calorie intake) and a control group, with measured outcomes showing weight loss in the CR group and variable impacts on V˙O2max and strength.
  • Results indicated that while absolute measures of V˙O2max and muscle strength decreased in the CR group, when adjusted for body mass, these values improved, suggesting that moderate CR may not negatively affect aerobic capacity in healthy adults.
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Children residing in urban, low-resource neighborhoods may be at increased risk for poor aerobic fitness and obesity. The objective of this collaborative project with an urban public school district was to quantify the combination of poor aerobic capacity and high percent body fat using FITNESSGRAM® Healthy Fitness Zone (HFZ) standards among urban, predominantly Black, public elementary school boys and girls. Measurements of aerobic capacity with the 20-m Progressive Aerobic Cardiovascular Endurance Run (PACER) test and body composition by bioelectrical impedance analysis were completed on 1,775 fourth and fifth grade students in 45 public elementary schools in St.

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