Publications by authors named "M U Inan"

Background: Intestinal ischemia/reperfusion (I/R) injury can occur in a wide variety of diseases and surgeries. If necessary, the blood flow should be restored, including re-anastomosis by removing the intestines with impaired circulation. In this process, anastomotic strength is as important as inflammatory responses and oxidative stress.

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Low-cost and safe vaccines are needed to fill the vaccine inequity gap for future pandemics. Pichia pastoris is an ideal expression system for recombinant protein production due to its cost-effective and easy-to-scale-up process. Here, we developed a next-generation SARS-CoV2 Omicron BA.

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Introduction: Primary immunodeficiency diseases (PIDs), are a growing group of rarely seen diseases. Various clinical conditions like autoimmunity, lymphoproliferative/malignant diseases, chronic lung and gastrointestinal system diseases have been identified which accompanies PIDs besides recurrent infections. However, there is a lack of information about accompanying cardiovascular diseases.

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Article Synopsis
  • Checkpoint inhibitors like atezolizumab are important immunotherapy drugs used to treat various cancers by targeting immune checkpoints.
  • This study focused on producing atezolizumab using a specialized monoclonal cell line from Chinese hamster ovary cells, aiming to establish a reliable production process.
  • After growing the cells in a bioreactor and purifying the antibody through chromatography, researchers compared the produced atezolizumab with the commercially available version to evaluate its characteristics.
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Addressing the critical shortage of mental health resources for effective screening, diagnosis, and treatment remains a significant challenge. This scarcity underscores the need for innovative solutions, particularly in enhancing the accessibility and efficacy of therapeutic support. Embodied agents with advanced interactive capabilities emerge as a promising and cost-effective supplement to traditional caregiving methods.

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