Publications by authors named "M U Ferraye"

Article Synopsis
  • Researchers tested deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) to treat freezing of gait (FOG) in Parkinson's disease (PD), noting varied patient responses possibly linked to electrode placement.
  • The study aimed to correlate the effects of DBS in the caudal mesencephalic reticular formation (cMRF) with patient outcomes, using a normalized brainstem coordinate system for accurate positioning.
  • Results indicated that the best effects for treating FOG were achieved with electrode contacts in the posterior cMRF, particularly near the pontomesencephalic junction, leading to recommendations for optimal DBS targeting.
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Objective: To assess, in a cross-sectional study, the feasibility and immediate efficacy of laser shoes, a new ambulatory visual cueing device with practical applicability for use in daily life, on freezing of gait (FOG) and gait measures in Parkinson disease (PD).

Methods: We tested 21 patients with PD and FOG, both "off" and "on" medication. In a controlled gait laboratory, we measured the number of FOG episodes and the percent time frozen occurring during a standardized walking protocol that included FOG provoking circumstances.

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Background: Freezing of gait (FOG) is a mysterious, complex and debilitating phenomenon in Parkinson's disease. Adequate assessment is a pre-requisite for managing FOG, as well as for assigning participants in FOG research. The episodic nature of FOG, as well as its multiple clinical expressions make its assessment challenging.

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