Publications by authors named "M Tzivras"
Background And Aim Of The Study: Although anal cancer represents a relatively uncommon malignancy, its incidence over the last five decades, has been reported as increased for both sexes, worldwide. Human papillomavirus (HPV) infection has been shown to be a major cause for its development. The aim of the present study is to report on clinical, epidemiological and virological data of squamous anal cancer in Greek patients.
View Article and Find Full Text PDFBackground: Acute pancreatitis is a form of inflammation with clinical features ranging from pancreatic inflammation to fatal systemic manifestations. The aim of this study was to clarify changes in lymphocyte subsets and alterations in the functioning of natural killer (NK) cells.
Patients And Methods: Forty-five patients were enrolled into the study; 35 with acute pancreatitis and systemic inflammatory response syndrome (SIRS) and 10 healthy subjects.
Article Synopsis
- Somatostatin and its analogs interact with five specific receptors (sstr1-5) found on endocrine tumors, while dopamine operates through five receptors (D1R-D5R), which have also been discovered in these tumors.
- In a study of gastroenteropancreatic neuroendocrine tumors (GEP-NETs), various tumor types were examined, revealing that 76.31% showed positive expression for somatostatin receptors, with sstr2A being the most common.
- The finding of high sstr2A and sstr2B expression suggests that these receptors could improve imaging and targeted therapy for GEP-NETs, and their co-expression with dopamine receptor D2R provides potential new treatment
Objective: Helicobacter pylori (H pylori) represents a potential initiator of cholesterol crystallization and it has been proposed that it is related to gallstone formation. In this study, any possible association between the H pylori identification in the mucosa of gallbladder and cholesterol gallstone formation was evaluated
Methods: Gallbladders containing pure or mixed cholesterol gallstones (cholelithiasis group, n = 89) and gallbladders without gallstones (control group, n = 42) were submitted to standard histopathological examination for H pylori detection, as well as to nested polymerase chain reaction amplification for H pylori DNA detection.
Results: Helicobacter pylori was identified in the gallbladder's epithelium in four patients with cholelithiasis and in two patients in the control group by histology.
Most pancreatic adenocarcinoma patients present with locally advanced or metastatic disease at diagnosis. in this retrospective study the authors evaluated the prognostic significance of the CEA and CA-19.9 serum tumor markers in advanced (unresectable) pancreatic cancer in correlation to other prognostic factors (demographic data, clinical parameters, treatment modality) and survival time using univariate and multivariate methods, in 215 patients with locally advanced (unresectable) or metastatic pancreatic adenocarcinoma.
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