Identifying preferred program delivery attributes for long-acting injectable cabotegravir-rilpvirine in three U.S. HIV clinics: A discrete choice experiment.

Background: Long-acting injectable cabotegravir and rilpivirine (CAB/RPV-LA) may overcome adherence barriers and provide treatment choice among people with HIV (PWH). However, little is known about the factors most likely to facilitate CAB/RPV-LA use.

Methods: We conducted a discrete choice experiment (DCE) at three urban U.

The sensor histidine kinase PhcS participates in the regulation of quorum sensing-dependent virulence genes in strain OE1-1.

Unlabelled: strain OE1-1 secretes methyl 3-hydroxymyristate (3-OH MAME) as a quorum-sensing (QS) signal. Strain OE1-1 senses the chemical by the sensor histidine kinase PhcS, leading to the activation of the LysR family transcriptional regulator PhcA. The activated PhcA controls the expression of QS-dependent genes responsible for QS-regulated phenotypes including virulence.

Sucrose and malic acid in the tobacco plant induce regulon in a phytopathogen .

Genes encoding a type III secretion system in are regulated by HrpB as an regulon and induced only in plants. This study aimed to identify the plant signals that induce the regulon and confirm the signal recognition mechanism. Signaling molecules that induce expression were screened using resting cells of the reporter strain.

Determining the optimal surface tracking area on the stereotactic mask in brain stereotactic radiosurgery using thermo-optical surface-guided radiotherapy.

Purpose: Surface-guided radiotherapy (SGRT) using ExacTrac Dynamic (EXTD) combines the optical surface with "thermal" imaging. We investigated the relationship between surface temperature changes and position errors detected by EXTD and identified the optimal surface tracking area (STA) on a stereotactic mask for brain stereotactic radiosurgery.

Methods: A phantom with a heat pad and a stereotactic mask over it was set up on the linac, and its surface was assigned to the STA.

Ultrasonic characterization of 3D-printed polymer objects.

3D printing technology, also known as Additive Manufacturing (AM), has revolutionized object prototyping, offering a simple, cost-effective, and efficient approach to creating structures with diverse spatial features. However, the mechanical properties of 3D-printed structures are highly dependent on the material type and manufacturing technique employed. In this study, ultrasonic testing methods were used to comprehensively characterize standard samples produced using two popular printing techniques: material extrusion and vat photopolymerization.