Recent studies suggest that glucocorticoid receptor (GR) activation can cause enzalutamide resistance in advanced prostate cancer (PCa) via functional bypass of androgen receptor (AR) signaling. However, the specific molecular mechanism(s) driving this process remain unknown. We have previously reported that the transcription factor TBX2 is over-expressed in castrate-resistant prostate cancer (CRPC).
View Article and Find Full Text PDFGastric teratomas are an extremely rare variety of teratomas in children. The aim of our series is to present the natural history and progression of the disease. Retrospective analysis of prospectively maintained data of all the gastric teratoma patients treated at our center was done from their electronic medical records.
View Article and Find Full Text PDFHepatocellular carcinoma (HCC), a liver cancer originating from hepatocytes, is a major health concern and among the most common malignancies worldwide. Sorafenib, approved by the U.S.
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