Temsirolimus in VEGF-refractory metastatic renal cell carcinoma.

Background: Temsirolimus is an i.v. administered inhibitor of mammalian target of rapamycin with activity in the first-line setting in poor-prognosis patients with metastatic renal cell carcinoma (RCC).

[Prognostic implications of biologic markers in intracranial meningiomas: 120 cases].

Unlabelled: The recurrence and progression of treated intracranial meningiomas highlights the problem of the type of follow-up that should be used and whether early complementary treatment is indicated. The aim of this study was to evaluate different biochemical markers involved in cell proliferation and transformation to identify new prognostic factors in intracranial meningiomas. Between 1989 and 2003, 120 intracranial meningiomas were studied biochemically.

Quality of life in adults diagnosed with familial adenomatous polyposis and desmoid tumor.

Purpose: The purpose of this study was to examine the health-related quality of life in a sample of Canadian adults diagnosed with familial adenomatous polyposis and desmoid tumor.

Methods: The study was conducted in two parts. Seven individuals participated in a focus group prior to a mail-out survey.