Ca signaling in cells begins with the opening of Ca channels in either the plasma membrane (PM) or the endoplasmic reticulum (ER) and results in a dramatic increase in the physiologically low (<100 nM) cytosolic Ca level. The temporal and spatial Ca levels are well regulated to enable precise and specific activation of critical biological processes. Ca signaling regulates pathogenic features of apicomplexan parasites like which infects approximately one-third of the world's population.
View Article and Find Full Text PDFThe use of pheromones, while common, remains underexplored in mosquito research. Understanding Aedes aegypti's mating behaviour and pheromones is crucial for expanding knowledge and advancing vector control strategies. Unlike other species, Aedes mosquitoes have adaptable mating behaviour, complicating the study of their communication mechanisms.
View Article and Find Full Text PDFPurpose: Cement augmentation is considered to improve the bone-implant construct stability in hip fragility fractures, additionally biomechanical studies show that cement augmentation improves the pull-out strength and increases resistance to failure. Thus far, the advantage of these technique used in a clinical scenario is yet to be determined METHODS: a randomized, multicenter, single-blinded clinical trial was conducted in patients aged 65 years or older who were admitted to two level I trauma centers with a fragility intertrochanteric hip fracture during September 2015 and December 2017. Patients were stratified into 2 groups: patients between 65 and 85 years and older than 85 years.
View Article and Find Full Text PDFEmployee strain is estimated to cost American companies as much as $500 billion in lost productivity annually, and a leading cause of workforce stress is disagreements with other people (Cook, 2017; Mental Health America, 2017). In this study, we investigate supervisor-subordinate value incongruence as a cause of employee strain. Specifically, this study examines the effect of supervisor-subordinate power distance orientation incongruence on the subordinate's job strain which, in turn, influences the subordinate's job performance.
View Article and Find Full Text PDFCOVID-19 has spread quickly to several countries following the initial outbreak of the disease. As a consequence, several measures have been taken to mitigate the virus spread worldwide. In the city of Florianópolis, in southern Brazil, a strict lockdown was implemented on 16 March 2020.
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