Links between accuracy and effectiveness of laboratory medicine equipment: use of the EUnetHTA core model to compare two analyzers by measuring HbA1c.

Objectives: In the field of Laboratory Medicine, the evolution of knowledge and the innovation of technologies are the basis of analytical and diagnostic progress, leading to the development of new solutions based on innovative technologies. However, these advances must be accompanied by evidence of appropriateness, diagnostic effectiveness, and organizational efficiency, considering the test's first impact on patient outcomes.

Methods: The Health Technology Assessment (HTA) is a valid management tool to support Laboratory Medicine professionals in assessing technologies and which is the most appropriate to adopt.

Customized cutoff limits for the sediMAX-2 automated analyzer reduce the number of urine culture tests.

Background: Urinary tract infections are highly prevalent in nosocomial and community settings. Their diagnosis, although costly and time-consuming, is crucial to avoid inappropriate treatments and/or clinical complications. In this context, automated analyzers have been developed and commercialized to screen and rule out negative urine samples.

An increased CDT camouflaged a monoclonal light chain gammopathy: An approach for diagnosis.

Introduction: Carbohydrate-deficient transferrin (CDT) is the most reliable indicator for the detection of chronic alcohol consumption. Recently, we have investigated a clinical case in which a concomitant monoclonal light chain gammopathy mimicked an increase of this biomarker.

Materials And Methods: A patient's serum was routinely examined by capillary electrophoresis (CE) for evaluation of CDT, and it was subsequently analysed through high-performance liquid chromatography (HPLC) to confirm the referred result.