Publications by authors named "M Traub"

Article Synopsis
  • Ceramides are important sphingolipids that play a crucial role in managing cellular metabolism, and six specific enzymes (CerS) are responsible for their synthesis.
  • C16 ceramide, linked to obesity and insulin resistance, has CerS6 as a potential drug target due to its specific action in these conditions.
  • New research using cryo-electron microscopy reveals how CerS6 works, showing that it uses a unique reaction mechanism and interacts with substances like the mycotoxin fumonisin B1, paving the way for future drug development.
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The estrus cycle in female rodents has been shown to affect a variety of physiological functions. However, little is known about its presumably thorough effect on auditory processing during the sleep-wake cycle and sleep deprivation. Vertex auditory evoked potentials (vAEPs) were evoked by single click tone stimulation and recorded during different stages of the estrus cycle and sleep deprivation performed in metestrus and proestrus in female rats.

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We present a detailed analysis of multiphysics simulation results to evaluate the threshold for catastrophic optical damage (COD) of high-power laser diodes under misaligned external optical feedback. Three different chip designs are investigated: the non-injecting mirror concept, the non-absorbing mirror concept and the introduction of an additional energy barrier within the waveguide near the front facet. Furthermore, a modification of the external resonator that promises a lower sensitivity towards misalignments is considered.

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Introduction: Wounds of the skin induced by irradiation involve a disruption of skin homeostasis and an increase in inflammation. Physiological renormalization treatment strategies using the molecules released from stem cells that restore proteostasis and regulate the immune system and reduce inflammation may be effective in treating skin conditions. Previous studies of severe radiation dermatitis found a significant reduction in symptoms using a combination product of the secretome from adipose mesenchymal stem cells and dermal fibroblasts, but mild radiation dermatitis has yet to be studied using this product.

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The spatial distribution of the optical feedback field in an external-cavity diode laser (ECDL) is an important parameter influencing its lifetime and filamentation. From a modeling point of view, the evaluation of the full diffraction integral is required to calculate the propagation of light through thick lenses such as fast axis collimation lenses or beam transformation systems used for high-power diode lasers. In this Letter, we illustrate an algorithm for the accelerated computation of the Rayleigh-Sommerfeld diffraction integral on a graphics processing unit.

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