Intra-dialytic blood oxygen saturation (SO): association with dialysis hypotension (the SOGLIA Study).

Background: Intradialytic hypotension (IDH) has a dramatic impact on the main outcomes of dialysis patients. Early warning of hemodynamic worsening during dialysis would enable preventive measures to be taken. Blood oxygen saturation (SO) is used for hemodynamic monitoring in the critical care setting and may provide useful information about IDH onset.

Brain cancer prognosis: independent validation of a clinical bioinformatics approach.

Translational and evidence based medicine can take advantage of biotechnology advances that offer a fast growing variety of high-throughput data for screening molecular activities of genomic, transcriptional, post-transcriptional and translational observations. The clinical information hidden in these data can be clarified with clinical bioinformatics approaches. We have recently proposed a method to analyze different layers of high-throughput (omic) data to preserve the emergent properties that appear in the cellular system when all molecular levels are interacting.

Joint analysis of transcriptional and post- transcriptional brain tumor data: searching for emergent properties of cellular systems.

Background: Advances in biotechnology offer a fast growing variety of high-throughput data for screening molecular activities of genomic, transcriptional, post-transcriptional and translational observations. However, to date, most computational and algorithmic efforts have been directed at mining data from each of these molecular levels (genomic, transcriptional, etc.) separately.

Polycystic ovarian disease: ultrasonic evaluation and correlations with clinical and hormonal data.

The size, shape, margins, and structure of the ovaries, as observed in 26 patients with polycystic ovarian disease were analyzed, and uterine/ovarian ratio (maximum antero-posterior diameter of uterine fundus divided for longitudinal diameter of ovary) was calculated. The maximum surface area of the organs ranged from 9.5 cm2 to 17.