Feasibility of a rapid dipstick antigen-capture assay for self-testing of travellers' malaria.

This open comparative study sought to determine whether, and with what level of instruction, travellers can successfully use and interpret the rapid whole blood malaria diagnostic test, ParaSight F. 160 visitors to the Zürich University Travel Clinic took part in the study. One group received written instructions only, while another group was given combined oral and written instructions on how to test their own blood for malaria infection and interpret a series of 5 prepared test strips.

[Idiopathic thrombocytopenic purpura: diagnosis and therapy in 46 patients].

The hematological and immunological data of 46 patients with idiopathic thrombozytopenic purpura (ITP) and their response to treatment are reported. The findings are as follows: (1) Antiplatelet antibodies (serum assays) cannot be recommended as a useful diagnostic approach in ITP. (2) Circulating immune complexes are demonstrable in 77% of our patients.

[Occurrence and clinical relevance of thrombocytosis].

Automated routine platelet counting in 18,602 patients revealed thrombocytosis (platelet count above 400,000/mm3) in 9% (n = 1602) of cases. In 32% of the patients with thrombocytosis an acute or chronic inflammatory process was found, 9% had a malignant tumor and 9% anemia. 6% were alcoholics and 6% had a myeloproliferative syndrome.

[The value of serum ferritin, serum iron and iron-binding capacity in the differential diagnosis of microcytic hypochromic anemia].

Ferritin, iron, total iron binding capacity and transferrin saturation were measured in the serum of 247 patients with microcytic hypochromic anemia. Differentiation into various categories of microcytic hypochromic anemia was based on clinical criteria and on the response to iron treatment. This produced 147 patients with iron deficiency anemia, 35 patients with anemia secondary to infection, 27 patients with anemia due to tumor and 38 patients with thalassemia.