Publications by authors named "M Tosti Balducci"

Article Synopsis
  • Several neurodegenerative diseases, like Huntington's and Parkinson's, are linked to harmful long polyglutamine (polyQ) tracts.
  • Researchers explored the effects of erucin (ERN), a natural compound found in rocket salad, and sulforaphane (SFN) in broccoli, on polyQ toxicity.
  • The study found that ERN protects against polyQ-induced toxicity by working through the AMPKα2 enzyme and the FOXO transcription factor, and also showed potential for reducing α-synuclein aggregates in Parkinson's disease, suggesting further research in mouse models is needed to assess its protective effects in humans.
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Objectives: The primary aims of this multicenter, prospective observational study were to investigate spiritual well-being, resilience, and psychosocial distress in an Italian sample of glioblastoma patients undergoing radiochemotherapy. The secondary aim was to explore the influence of demographic, clinical, and psychological characteristics on survival.

Methods: The assessment was conducted only once, within the first week of radiochemotherapy treatment.

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Independent of overall achievement, girls' intraindividual academic strength is typically reading, whereas boys' strength is typically mathematics or science. Sex differences in intraindividual strengths are associated with educational and occupational sex disparities in science, technology, engineering, and mathematics (STEM) fields. Paradoxically, these sex differences are larger in more gender-equal countries, but the stability of this paradox is debated.

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It is challenging to make nocturnal observations of the natural behaviour of flower-visiting moths as they are highly sensitive to visible artificial light sources. One solution, implemented here, is to use specially-adapted close-focusing camera traps that rely on infrared wavelengths for detection and illumination of small insect subjects. We investigated the pollination system of Bonatea saundersiodes, a rare African terrestrial orchid that is phylogenetically nested in the large Habenaria clade.

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Fucoxanthin is the most abundant carotenoid found in marine brown algae that exhibits several healthy properties. Dietary fucoxanthin is metabolized in the intestine, plasma, and other tissues to various metabolites, including fucoxanthinol. In this regard, the contribution of fucoxanthinol to the healthy properties of its precursor, fucoxanthin, against pathogenetic events associated with neurodegenerative diseases remains unexplored.

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