Comparison of oxidative stress status in the kidney tissue of male rats treated with paraquat and nanoparaquat.

The study aimed to compare the oxidative stress status in the kidney tissue of rats treated with paraquat and nanoparaquat. The levels of oxidative stress markers, including malondialdehyde (MDA), total antioxidant capacity (TAC), and thiol groups (TTG), were measured in the kidney tissue samples. A total of forty male Wistar rats were randomly assigned to eight groups, each consisting of five rats: a control group, a paraquat (PQ) group, an N-acetylcysteine (NAC) group, groups receiving nanoparaquat α and β (α and β), groups receiving PQ and NAC (PQ + NAC), and groups receiving nanoparaquat α and β with NAC (+ NACα and β).

AI-Assisted Post Contrast Brain MRI: Eighty Percent Reduction in Contrast Dose.

Objectives: In the context of growing safety concerns regarding the use of gadolinium-based contrast agents in contrast-enhanced MRI, there is a need for dose reduction without compromising diagnostic accuracy. A deep learning (DL) method is proposed and evaluated in this study for predicting full-dose contrast-enhanced T1w images from multiparametric MRI acquired with 20% of the standard dose of gadolinium-based contrast agents.

Materials And Methods: This multicentric prospective study leveraged multiparametric brain MRIs acquired between March and July 2024.

Magnetoresponsive liposomes applications in nanomedicine: A comprehensive review.

Safe and effective cancer therapy requires a suitable nanocarrier that can target particular sites, such as cancer cells, in a selective manner. With the tremendous growth in nanotechnology, liposomes, among various competing nanocarriers, have shown promising advances in cancer therapy. Magnetic nanoparticles and metal ions are wide-reaching candidates for conferring magnetic properties and for incorporation into liposomes.