Mycobacterial β-carbonic anhydrases: Molecular biology, role in the pathogenesis of tuberculosis and inhibition studies.

Mycobacterium tuberculosis (Mtb), which causes tuberculosis (TB), is still a major global health problem. According to the World Health Organization (WHO), TB still causes more deaths worldwide than any other infectious agent. Drug-sensitive TB is treatable using first-line drugs; treatment of multidrug-resistant (MDR) and extensively drug-resistant (XDR) TB requires second- and third-line drugs.

The effect of early childhood non-nutritive sucking behavior including pacifiers on malocclusion: a randomized controlled trial.

Background/rationale: Systematic reviews on the effects of pacifiers on occlusion have highlighted the need for quality RCTs.

Trial Design: Single region, three parallel-armed, prospective, randomized controlled trial.

Objectives: To investigate the correlations between early childhood non-nutritive sucking habits and malocclusion.

Effects of headgear timing on dental arch changes from 7 to 18 years of age: a follow-up study.

Background: Dental arch effects after cervical headgear (CHG) treatment have been researched from several different perspectives. However, the long-term effects of CHG timing are still unknown.

Objectives: To analyse the long-term effects of CHG timing on dental arches.

Associations between pain-related temporomandibular disorders and dental anxiety at 46 years of age in the Northern Finland Birth Cohort 1966.

Objectives: The aims were (1) to study the association between dental anxiety (DA) and temporomandibular disorders (TMDs) and whether subgroups formed differ in psychological symptoms and pain sensitivity in the Northern Finland Birth Cohort 1966 and (2) to confirm the factor structure of the Hopkins Symptom Checklist-25 assessing psychological symptoms.

Materials And Methods: Data were acquired using questionnaires and clinical examinations at age 46 years ( = 1889). Dental anxiety was assessed with Modified Dental Anxiety Scale (MDAS).

The relation of temporomandibular disorders with oral health-related quality of life in the Northern Finland Birth Cohort 1966.

Objective: This study aimed to evaluate the association between temporomandibular disorders (TMD) and oral health-related quality of life (OHRQoL) in an adult population.

Methods: The data included 1,768 adults 46 years of age in the Northern Finland Birth Cohort 1966 (NFBC1966) study. The symptoms, signs and diagnoses of TMD were assessed using a modified protocol of the Diagnostic Criteria for TMD (DC/TMD) and validated questionnaires.