Publications by authors named "M Tolone"
Backgrounds And Aims: Submental skin laxity (SSL), manifesting as sagging skin and double chin, can significantly affect patients' self-perception and social interactions. While surgical treatments exist, non-invasive methods are increasingly sought for their minimal recovery time. This study assesses the safety and effectiveness of a novel microwave-based device for treating SSL, aiming to provide long-term improvements in skin tightness and appearance.
View Article and Find Full Text PDFGenome-Wide Scan for Selective Sweeps Reveals Novel Loci Associated with Prolificacy in Iranian Sheep Breeds in Comparison with Highly Prolific Exotic Breed.
Animals (Basel)
November 2024
Article Synopsis
- - The study analyzed 837 ewes from specific Iranian sheep breeds and one Greek breed to explore genetic factors related to prolificacy using OvineSNP50K arrays.
- - Researchers applied statistical analyses to identify 19 genomic regions across various chromosomes that are under selection for prolificacy traits.
- - Bioinformatic analysis indicated these regions contain candidate genes tied to prolificacy, milk yield, and body weight, suggesting opportunities for future research on genetic links to sheep prolificacy traits.
Article Synopsis
- The emergence of biotechnological drugs has transformed the treatment of moderate-to-severe atopic dermatitis (AD), focusing on anti-interleukin (IL)-13 therapies.
- A systematic review highlighted tralokinumab's effectiveness and safety, showing significant improvements in various clinical metrics for patients inadequately managed by previous therapies.
- While tralokinumab has demonstrated promising results and a favorable safety profile, more extensive studies are needed to confirm its long-term benefits compared to existing treatments.
Visna/Maedi virus (VMV) is lentiviral disease of sheep responsible for severe production losses. Multiple genomic regions associated with infection were reported indicating genetic complexity. In this study, a combined genome-wide approach using a high-density SNP array has been performed, comparing VMV-infected ( = 78) and non-infected ( = 66) individuals of the Valle del Belice breed.
View Article and Find Full Text PDFIntroduction: Paratuberculosis (PTB) is a worldwide chronic, contagious enteric disease caused by subsp. (MAP) mainly affecting ruminant species. PTB is a WOAH-listed disease with direct and indirect economic losses in the livestock sector, negative impact on animal welfare and significant public health concerns.
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