Publications by authors named "M Tjioe"
Background: During the COVID-19 pandemic, psoriasis care underwent significant changes in consultation methods and treatment management. However, comprehensive data on these changes and patient perceptions are limited.
Aims: To evaluate the pandemic's implications on psoriasis patients, focusing on access to information, consultation methods, patient satisfaction, disease control assessment, and treatment management changes.
Article Synopsis
- The study investigates the impact of psoriasis on patients' work and daily life activities as they start using biological treatments.
- Data from 194 patients showed that after beginning treatment, disease activity significantly decreased, yet work participation remained lower than the general population.
- Although employed patients exhibited improved productivity, nearly half still faced challenges in daily activities, with no significant changes observed over time.
We present avidity sequencing, a sequencing chemistry that separately optimizes the processes of stepping along a DNA template and that of identifying each nucleotide within the template. Nucleotide identification uses multivalent nucleotide ligands on dye-labeled cores to form polymerase-polymer-nucleotide complexes bound to clonal copies of DNA targets. These polymer-nucleotide substrates, termed avidites, decrease the required concentration of reporting nucleotides from micromolar to nanomolar and yield negligible dissociation rates.
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- The study examines the risk of SARS-CoV-2 infection in psoriasis patients undergoing different treatments, specifically comparing biologics, systemic conventional therapies, and topical therapies.
- Among 551 patients, only 10.7% were found to have had a SARS-CoV-2 infection, with no significant increase in infection risk for those using biologics.
- The results showed a low hospitalization rate (0.7%) and a mortality rate of 0.32% across all treatment groups, indicating that psoriasis treatment does not significantly affect COVID-19 severity.