Feasibility and safety of dilatational tracheotomy using the rigid endoscope: a multicenter study.

Background: Fiberoptic tracheo-bronchoscopy is the most commonly used procedure for percutaneous dilational tracheotomy (PDT). However, PDT can be associated with major complications, including death. Furthermore it is unclear, whether the tracheal ring fractures may contribute to the development of tracheal stenosis after PDT nor whether tracheal ring fractures can be prevented by using a rigid endoscope for this procedure.

[Parent-child interaction during activity and rest behavior of inhabitants of Trobriand Islands (Papua New Guinea)].

Sleep/activity patterns were continuously registered using microelectronic actometers on inhabitants of Tauwema (Papua New Guinea) who represent a traditionally living society. Results of analysis of parent-infant interactions of 4 families with infants of 1, 2, 5, and 11 months of age are presented. Results of power spectral analysis suggest that time patterns of mother-infant interactions are changing with the infants AE age.

Kinetics of allopurinol after single intravenous and oral doses. Noninteraction with benzbromarone and hydrochlorothiazide.

An high-pressure liquid chromatographic method was used to measure allopurinol and oxipurinol in plasma and urine in 6 healthy volunteers after a single intravenous or oral dose of allopurinol. The influence of coadministered benzbromarone and hydrochlorothiazide on the pharmacokinetics of allopurinol and oxipurinol was also investigated. After intravenous injection of allopurinol 300 mg the plasma disappearance was biexponential, with a mean distribution half-life of 2.