Publications by authors named "M Timko"

Plant species can accumulate secondary metabolites in optically pure form or, occasionally, as enantiomeric mixtures. Interestingly, enantiomers of the same molecule can confer different biological activities. In tobacco (Nicotiana tabacum L.

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Article Synopsis
  • * After reviewing 927 studies, 14 randomized controlled trials were included, with 79% showing significant reductions in neuropathic pain scores when treated with cannabinoids compared to a placebo.
  • * Results indicate that cannabis-based medicines not only alleviate neuropathic pain but also improve secondary outcomes like sleep, sensory symptoms, and overall quality of life, suggesting their potential as a treatment option.
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The molecular structure of hydrochars produced from C-enriched glucose under various conditions has been elucidated based on advanced one- and two-dimensional (2D) H-C and C-C solid-state nuclear magnetic resonance (NMR) with spectral editing. Regardless of synthesis conditions, hydrochars consist mostly of oxygen-substituted arene rings (including diphenols) and furans connected by alkyl linkers rich in ketones. Cross-linking nonprotonated and methyne (C-H) alkyl carbons have been identified through spectrally edited 2D NMR.

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Current solutions to global challenges place tension between global benefits and local impacts. The result is increasing opposition to implementation of beneficial climate policies. Prioritizing investment in projects with tangible local benefits that also contribute to global climate change can resolve this tension and make local communities' partners instead of antagonists to change; the approach advocated is a new take on "thinking globally, acting locally".

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