Publications by authors named "M Tikly"
Pulmonary manifestations of the idiopathic inflammatory myopathies in a South African population.
Afr J Thorac Crit Care Med
October 2024
Article Synopsis
- Pulmonary complications are a significant health issue for patients with idiopathic inflammatory myopathies (IIMs) in South Africa, causing high morbidity and mortality rates.
- A study reviewed clinical records of adult IIM patients with respiratory issues in a tertiary care facility, revealing that most patients suffered from dermatomyositis and exhibited symptoms like dyspnoea and dry cough.
- Interstitial lung disease (ILD) emerged as the most common complication, with associations found between respiratory symptoms and poorer lung function outcomes over time.
Article Synopsis
- * Results showed that while many lab tests and medications were available, there were significant regional differences in access, particularly in East and West Africa.
- * Key issues identified included long turnaround times for test results and patients often having to self-fund medical expenses, which hindered timely diagnosis and treatment.
Patient journey, disease burden, and functional disability in patients with axial spondyloarthritis in South Africa: results of International Map of Axial Spondyloarthritis (IMAS).
Clin Rheumatol
November 2024
Objective: To assess the unmet needs of South Africans with axial spondyloarthritis (axSpA) focusing on the patient journey, functional disability, and health-related quality of life.
Methods: One hundred forty-six South African axSpA patients completed the International Map of Axial Spondyloarthritis (IMAS) online survey. Patient journey, functional disability, activities of daily living, and psychological stress were analyzed in relation to socio-demographic characteristics, disease activity, diagnostic delay, extra-musculoskeletal manifestations, and drug therapy.
Introduction Comorbidities in systemic lupus erythematosus (SLE) impact negatively on health-related quality of life (HRQoL) and life expectancy. We investigated the frequency and spectrum of comorbidities in privately insured South Africans with SLE. Methods The data of SLE patients based on International Classification of Diseases, Tenth Revision (ICD-10) codes and insured with Discovery Health Medical Scheme (DHMS), South Africa, aged ≥16 years at diagnosis and with ≥6 months of follow-up were reviewed.
View Article and Find Full Text PDFBackground And Objectives: In SSc, ILD is a major cause of morbidity and mortality. We aimed to investigate the performance of DLCO (diffusing capacity of lung carbon monoxide) and FVC (forced vital capacity) delta change (Δ) and baseline values in predicting the development of SSc-ILD.
Methods: Longitudinal data of DLCO, FVC, and ILD on the HRCT of SSc patients from the EUSTAR database were evaluated at baseline (t) and after 12 (±4) (t) and 24 (±4) (t) months.