Publications by authors named "M Tierney"
Article Synopsis
- The study examined the career trajectories of 167 microsurgeons who completed their fellowships from 2016 to 2020, finding that 92.2% initially practiced microsurgery, with many entering academia.
- About 31.4% of these surgeons switched jobs within five years, with a notable 58% changing their practice settings, while factors like gender and training did not significantly impact job changes.
- Those in academic positions were more likely to switch jobs, and having a microsurgery fellowship was linked to a higher likelihood of remaining in academia after a job change.
Generation of induced pluripotent cells (hiPSCs)-derived skeletal muscle progenitor cells (SMPCs) holds great promise for regenerative medicine for skeletal muscle wasting diseases, as for example Duchenne Muscular Dystrophy (DMD). Multiple approaches, involving ectopic expression of key regulatory myogenic genes or small molecules cocktails, have been described by different groups to obtain SMPC towards cell-transplantation as a therapeutic approach to skeletal muscle diseases. However, hiPSCs-derived SMPC generated using transgene-free protocols are usually obtained in a low amount and resemble a more embryonal/fetal stage of differentiation.
View Article and Find Full Text PDFNearly 50% of the U.S. population struggles with a mental health or substance use disorder in their lifetime, yet a substantial number are unable to receive treatment or are undertreated due to significant shortages and disparities in the mental health workforce.
View Article and Find Full Text PDFBackground And Objective: Owing to the expansion of treatment options for metastatic hormone-sensitive prostate cancer (mHSPC) and an appreciation of clinical subgroups with differential prognosis and treatment responses, prognostic and predictive biomarkers are needed to personalize care in this setting. Our aim was to evaluate a multimodal artificial intelligence (MMAI) biomarker for prognostic ability in mHSPC.
Methods: We used data from the phase 3 CHAARTED trial; 456/790 patients with mHSPC had evaluable digital histopathology images and requisite clinical variables to generate MMAI scores for inclusion in our analysis.