Publications by authors named "M Thumm"
Article Synopsis
- - Macroautophagy is a complex process that can lead to cell death, influenced by various cell types and stressors, while ferroptosis is a specific kind of cell death related to lipid damage and iron dependency.
- - Certain types of autophagy, like ferritinophagy and lipophagy, play a role in triggering ferroptotic cell death by degrading protective proteins, whereas others, such as reticulophagy, help protect cells from this damage.
- - The review seeks to clarify the relationship between autophagy and ferroptosis, focusing on defining terms, outlining key components, discussing experimental techniques, and providing interpretation guidelines for ongoing research.
In this paper, we present the design and commissioning results of the upgraded collective Thomson scattering diagnostic at the Wendelstein 7-X stellarator. The diagnostic has a new radiometer designed to operate between the second and third harmonics of the electron cyclotron emission from the plasma at 171-177 GHz, where the emission background has a minimum and is of order 10-100 eV. It allows us to receive the scattered electromagnetic field with a significantly improved signal-to-noise ratio and extends the set of possible scattering geometries compared to the case of the original instrument operated at 140 GHz.
View Article and Find Full Text PDFThe putative phospholipase Atg15 is required for the intravacuolar lysis of autophagic bodies and MVB vesicles. Intracellular membrane lysis is a highly sophisticated mechanism that is not fully understood. The amino-terminal transmembrane domain of Atg15 contains the sorting signal for entry into the MVB pathway.
View Article and Find Full Text PDFAtg18, Atg21 and Hsv2 are homologous β-propeller proteins binding to PI3P and PI(3,5)P. Atg18 is thought to organize lipid transferring protein complexes at contact sites of the growing autophagosome (phagophore) with both the ER and the vacuole. Atg21 is restricted to the vacuole phagophore contact, where it organizes part of the Atg8-lipidation machinery.
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