Publications by authors named "M Tharmaratnam"
Article Synopsis
- A study was conducted to evaluate the effectiveness of multiparametric magnetic resonance imaging (mpMRI) in identifying clinically significant prostate cancer (csPCa) in real-world clinical settings, particularly among men with elevated prostate-specific antigen (PSA) levels or abnormal examinations.
- The study included 2,642 men from ten sites and found that mpMRI had a high sensitivity (87.3%) and negative predictive value (87.5%) for diagnosing csPCa, although the specificity and positive predictive value were lower (around 50%).
- Using PSA density thresholds improved the diagnostic accuracy, with sensitivity and negative predictive values reaching as high as 96.6% when applying a specific PSA density threshold to low MRI scores. *
Chikungunya infection--an emerging disease in Malaysia.
Southeast Asian J Trop Med Public Health
September 2001
Many countries neighboring Malaysia have reported human infections by chikungunya virus, a mosquito-borne togavirus belonging to the genus Alphavirus. However, although there is serological evidence of its presence in Malaysia, chikungunya virus has not been known to be associated with clinical illness in the country. An outbreak of chikungunya virus occurred in Klang, Malaysia, between December 1998 and February 1999.
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