Bioactive chitosan based coating incorporated with essential oil to inactivate foodborne pathogen microorganisms and improve quality parameters of beef burger.

The aim of this study is to assess the impacts of chitosan (CH) coating with oregano essential oil (OEO) and thyme essential oil (TEO) (0.5%-1.0%; ) on the foodborne pathogens and physicochemical parameters of beef burger during refrigerated storage.

Prevalence and Association of Malaria With ABO Blood Groups in Bosaso City, Puntland, Somalia: A Cross-Sectional Study.

Background And Aims: Malaria remains a global health concern, with an estimated 249 million cases annually and 2.2 billion people at risk of infection. This study aimed to investigate the association between malaria species and ABO blood groups and identify the relationship between ABO blood groups and parasitemia.

Vaccination coverage and its associated factors among children under-5 in Somalia.

Objectives: Despite global efforts to improve vaccination, the coverage of completing basic immunization (BCG, Polio 3, DPT 3, and Measles vaccines) remains unsatisfactory in Somalia. Limited research exists on the determinants influencing immunization among under-5 Somali children, highlighting the novelty of this study. This study aims to identify the coverage and factors influencing the coverage of complete basic immunization among under-5 Somali children.

Three-dimensional markerless surface topography approach with convolutional neural networks for adolescent idiopathic scoliosis screening.

Adolescent idiopathic scoliosis (AIS) is a three-dimensional lateral and torsional deformity of the spine, affecting up to 5% of the population. Traditional scoliosis screening methods exhibit limited accuracy, leading to unnecessary referrals and exposure to ionizing radiation from x-ray examinations. The 3D markerless surface topography (ST) technique quantifies trunk asymmetry and can be a potential scoliosis screening tool.

Impact of Cancer-Associated PKM2 Mutations on Enzyme Activity and Allosteric Regulation: Structural and Functional Insights into Metabolic Reprogramming.

Mammalian pyruvate kinase M2 (PKM2) is a key regulator of glycolysis and is highly expressed in proliferative tissues including tumors. Mutations in PKM2 have been identified in various cancers, but their effects on enzyme activity and regulation are not fully understood. This study investigates the structural and functional effects of cancer-associated PKM2 mutations on enzyme kinetics, allosteric regulation, and oligomerization.