Objective: Peripheral nerve blocks in hand surgery.
Indications: Short operations on the hand.
Contraindications: Long operations, polyneuropathy, local anesthesia allergy.
Objective: Intravenous regional anesthesia.
Indications: Short duration hand operations.
Contraindications: Open wounds, lengthy operations, local infections, polyneuropathy, Raynaud syndrome, allergy to local anesthetics.
In aging population, postmenopausal osteoporosis and decline of musculoskeletal function, referred to as "frailty syndrome" lead to loss of bone and muscle, causing falls, and fall-related injuries. To limit the impact of this portentous duo, simultaneous treatment of both is needed. Urocortin (UCN) has been reported to improve osteoporotic bone properties while its effect on muscle has not been addressed yet.
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