Comparative study of management strategies for immune checkpoint inhibitor-induced inflammatory arthritis: rheumatologists versus oncologists.

Background: Immune checkpoint inhibitors (ICIs) have significantly improved cancer treatment outcomes but are associated with immune-related adverse events (irAEs), such as inflammatory arthritis (ir-IA). Management of ir-IA is evolving, with corticosteroids as the primary treatment, though some cases require steroid-sparing agents.

Aims: This study aimed to compare initial mean prednisolone doses and disease persistence over 12 months in patients with rheumatoid arthritis (RA)-like ir-IA managed by rheumatologists or oncologists.

Anti-synthetase syndrome associated interstitial lung disease after combination dual immune checkpoint inhibition.

Immune checkpoint inhibitors (ICIs) unleash potent anti-tumour responses but with frequent off-target immune-mediated adverse events (irAE). ICIs can induce a spectrum of rheumatologic manifestations including inflammatory arthritis, Sjögren's syndrome, scleroderma and systemic lupus erythematosus. Here, we describe a case of antisynthetase syndrome associated interstitial lung disease (ILD) following dual Programmed Cell Death 1 and Cytotoxic T Lymphocyte-Associated Protein 4 checkpoint inhibition in a patient with metastatic melanoma.

Survey of Australasian Renal and Rheumatology Specialists investigating topical NSAID use and adverse renal outcomes.

Introduction: A survey investigated physician reported use, prescribing practices and adverse renal events of topical NSAIDs.

Method: This survey was sent to members of the Australian Rheumatology Association and the Australian and New Zealand Society of Nephrology.

Results: Sixty physicians responded, 55% (n = 33) were nephrologists; 45% (n = 27) rheumatologists.

A survey on the beliefs and knowledge of gout management in new medical graduates - New South Wales, Australia.

Aim: To assess the beliefs and knowledge of gout management in new medical graduates.

Method: A survey on gout management was sent to new medical graduates during their orientation week, New South Wales, Australia.

Results: Of 15 hospital networks, 11 agreed to participate.

A survey of the assessment and management of gout in general practitioners and medical officers within the Illawarra Network, Australia.

Aim: To review the assessment and management of gout by general practitioners (GPs) and medical officers (MOs) within the Illawarra Network, Australia.

Method: A survey was sent to GPs and MOs within the Illawarra Network.

Results: Of 110 GPs, 45 responded.