Comparative Genome Analysis of Canine Isolates.

: The One Health approach is crucial for managing and controlling the spread of antimicrobial resistance. is a recently identified bacterial species that seems to be a component of the oral microbiota of dogs; however, its pathogenic nature is questionable. : In this study, the antibacterial susceptibility of isolates was determined using the disk diffusion and broth microdilution methods.

Examination of the Virulence of Serovar 16 in Pigs.

Different virulence variants of are involved in the etiology of porcine pleuropneumonia. The purpose of the present trial was examination of the virulence of the A-85/14 strain, the type strain of serovar 16, in an animal challenge experiment. Thirty 12-week-old piglets seronegative for were allocated into three trial groups each of 10 animals, and they were infected intranasally with 10, 10, or 10 colony forming units (cfu) of the strain, respectively.

Establishment of a challenge model in 5-week-old piglets.

Introduction: is an emerging swine pathogen with high prevalence worldwide. The main lesions caused are arthritis and polyserositis, and the clinical manifestation of the disease may result in significant economic losses due to decreased weight gain and enhanced medical costs. We aimed to compare two challenge routes to induce infection using the same clinical isolate.

Tetrabromobisphenol A and Diclazuril Evoke Tissue-Specific Changes of Thyroid Hormone Signaling in Male Thyroid Hormone Action Indicator Mice.

Thyroid hormone (TH) signaling is a prerequisite of normal tissue function. Environmental pollutants with the potential to disrupt endocrine functions represent an emerging threat to human health and agricultural production. We used our Thyroid Hormone Action Indicator (THAI) mouse model to study the effects of tetrabromobisphenol A (TBBPA; 150 mg/bwkg/day orally for 6 days) and diclazuril (10.

Comparative Efficacy in Challenge Dose Models of a Toxin Expressing Whole-Cell Vaccine against Eight Serovars of in Pigs.

is a major economically significant bacterial respiratory pig pathogen, and whole cell vaccines are used to prevent disease. However, there is little data available on multi-serovar whole cell vaccine protection. Therefore, we determined the protective efficacies of a whole-cell serovar 1 and 2 vaccine comprising ApxI-III toxins (C-vaccine, Coglapix, Ceva, France) against serovars 1, 2, 4, 5, 6, 7, 9/11, and 13.