Publications by authors named "M Tello"
Article Synopsis
- Multiple sclerosis (MS) often results in debilitating fatigue, impacting over 80% of patients and their quality of life and independence.
- This study aims to identify and evaluate patient-reported outcomes (PROs) that specifically measure fatigue in MS patients, focusing on their psychometric properties and risk of bias.
- The review included 34 studies, highlighting a mix of low and high risk levels in terms of measurement reliability, with many studies showing a low risk for certain properties like internal consistency and criterion validity, but concerns about bias in others.
Systemic lupus erythematosus (SLE) is an autoimmune disease, the pathophysiology and genetic basis of which are incompletely understood. Using a forward genetic screen in multiplex families with SLE, we identified an association between SLE and compound heterozygous deleterious variants in the non-receptor tyrosine kinases (NRTKs) and . Experimental blockade of ACK1 or BRK increased circulating autoantibodies in vivo in mice and exacerbated glomerular IgG deposits in an SLE mouse model.
View Article and Find Full Text PDFThis study presents the effect of natural zeolite (NZ) on a nitrifying sequencing batch reactor for removing ibuprofen (IBP) and diclofenac (DFC) in the long term, including kinetics and microbial community. The research was conducted in two 2 L liquid-volume bioreactors, one with 5 g/L of NZ. Nitrogen load rates ranging between 5.
View Article and Find Full Text PDFObjective: Opioid use disorder (OUD) can be effectively treated with buprenorphine maintenance. Recent changes in federal policy have removed the requirement for physicians to complete additional training to apply for a Drug Enforcement Administration (DEA) waiver to prescribe buprenorphine. At that time, few primary care providers (PCPs) had completed the training for a DEA waiver to prescribe buprenorphine.
View Article and Find Full Text PDF[The Metabolic syndrome and metabolic characteristics in blood donors].
Rev Fac Cien Med Univ Nac Cordoba
June 2024
Introduction: Metabolic syndrome (MS) is associated with increased cardiovascular risk. Blood donors are an apparently healthy population in which certain cardiometabolic characteristics are not evaluated in their selection, and there is limited information on their presence.
Aim: To determine the frequency of metabolic syndrome and its metabolic characteristics in blood donors.