Publications by authors named "M Teletin"
Article Synopsis
- The study focuses on male fertility preservation (FP) through sperm banking for men aged 15-49 diagnosed with testicular cancer (TC) or lymphomas (L) in France in 2018.
- It analyzed data from the French National Cancer Institute and sperm banking centers, estimating sperm banking rates of 41% for TC, 40% for Hodgkin L, and 7% for non-Hodgkin L among diagnosed men.
- The findings suggest a need for improved patient education and awareness to increase sperm banking rates and assess factors leading to the lack of sperm preservation before gonadotoxic treatments.
Background: Cancer treatments of the last decades improve the survival rate of children and adolescents. However, chemo- and radiotherapy result in gonadal damage, leading to acute ovarian failure and sterility. The preservation of fertility is now an integral part of care of children requiring gonadotoxic treatments.
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- Testicular germ cell tumors (TGCT) are the most common cancer in young men and their incidence has significantly increased over the past 40 years, prompting this study to investigate the link between certain occupations and TGCT risk in men aged 18-45.
- The TESTIS study, conducted in metropolitan France from 2015 to 2018, included 454 TGCT cases and 670 controls, collecting comprehensive job histories, and analyzed the data using statistical methods to estimate odds ratios for different occupations.
- Results indicated a higher TGCT risk in agricultural workers, salesmen, and electrical fitters, suggesting the need for further research to uncover specific agents or chemicals contributing to this increased risk in these professions.
It has been established for almost 30 years that the retinoic acid receptor (RAR) signalling pathway plays essential roles in the morphogenesis of a large variety of organs and systems. Here, we used a temporally controlled genetic ablation procedure to precisely determine the time windows requiring RAR functions. Our results indicate that from E8.
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