Tear LTC4 levels in patients with subclinical contact lens related giant papillary conjunctivitis.

We determined the tear levels of LTC4 in contact lens wearers who had minimal irritative symptoms and signs suggesting subclinical conjunctival abnormalities and the possible development of giant papillary conjunctivitis (GPC). We examined 25 patients wearing rigid gas permeable lenses. Ten of the contact lens wearers had minimal irritative symptoms and nonspecific papillary hypertrophy, and 15 patients had no symptoms.