Two new 4-phenylcoumarins, mesulepidotins A () and B (), one new 4-propylcoumarin, mesulepidotin C (), and one known 4-phenylcoumarin () were isolated from stem barks. The structures of 4-propyl- and 4-phenylcoumarins were identified by analysing 1D and 2D NMR spectra combined with high-resolution ESIMS data. Compounds were assayed to MCF-7 and HeLa cells for their cytotoxic activity.
View Article and Find Full Text PDFThree novel dihydrochalcones, flemilineatins C-E (), and two known flavanones () were isolated from (L.) W.T.
View Article and Find Full Text PDFAn undescribed dihydrostilbene, macajavanicin D (), and three known analogs, malayheyneiin A () and laevifolins A-B (-), were isolated from (Blume) Müll. Arg. leaves.
View Article and Find Full Text PDFPak J Biol Sci
November 2023
<b>Background and Objective:</b> The trash produced by boiling silkworm cocoons during the degumming process still retains useful amino acids, such as sericin and fibroin, that can repair skin damage caused by exposure to ultraviolet light. This study seeks to examine the impact of utilising degumming silkworm cocoons (DSC) gel, derived from boiling waste, on the healing process of rat skin that has been subjected to Ultraviolet (UV) light, as well as the determination of the Sun Protection Factor (SPF) value. <b>Materials and Methods:</b> The research used a Completely Randomized Design (CRD) consisting of 5 treatment groups, namely the positive control, avobenzone, the group without avobenzone and DSC gel and the administration of DSC gel at 20, 40 and 60% for 14 days.
View Article and Find Full Text PDFThree new dihydrochalcones: artoserichalcone A-C (), were isolated from the leaves of . The structures of compounds were determined based on NMR spectrum (H, C, and 2D) and HRESIMS spectroscopic analysis. Compounds () and () showed active antimalarial activity with IC values of 16.
View Article and Find Full Text PDF