Publications by authors named "M Takemura"
Background: Anemia in patients with cancer negatively affects their quality of life and cancer outcomes. However, most patients with chemotherapy-induced anemia (CIA) are not appropriately evaluated or treated, and the prevalence of iron deficiency anemia (IDA) in CIA remains unclear.
Methods: We retrospectively reviewed the electronic records of patients with gynecological cancer in two tertiary hospitals, between March 2023 and July 2023, and evaluated their anemia status.
The human intestinal microbiota that comprise over 1,000 species thrive in dark and anaerobic environments. They are recognized for the production of diverse low-molecular-weight metabolites crucial to human health and diseases. Carotenoids, low-molecular-weight pigments known for their antioxidative activity, are delivered to humans through oral intake.
View Article and Find Full Text PDFArticle Synopsis
- - Dasatinib is a medication used to treat chronic myeloid leukemia (CML), but some patients develop resistance due to high levels of the ABCG2 protein in their cancer cells.
- - A study involving 65 CML patients found that those taking the xanthine oxidase inhibitor febuxostat alongside dasatinib had better treatment outcomes, with significantly higher rates of early and major molecular response.
- - Laboratory experiments showed that febuxostat can lower cell viability and increase dasatinib levels in CML cells, suggesting it helps enhance dasatinib's effects by reducing ABCG2's ability to eject the drug from cells, which may offer new ways to tackle TKI resistance in CML treatment. *
Objectives: This study aimed to provide evidence regarding the clinical significance of assessing intrinsic capacity (IC).
Design: Longitudinal study.
Setting: Frailty clinic.
We have developed a new observation chamber for -infected to create dynamic visual teaching materials for virus education suitable for high school and university biology courses. We conducted experiments and captured a movie showcasing the infection process of cells by mimiviruses. In this educational film, we successfully recorded the active movement of healthy cells across the surface of a culture flask under an agarose gel.
View Article and Find Full Text PDF