Publications by authors named "M Tachezy"
Article Synopsis
- Researchers developed a novel risk score using molecular markers to predict survival in colorectal cancer patients, moving beyond traditional histopathological methods.
- The study analyzed 1791 patients using immunohistochemistry to measure the levels of H2BUB1, RBM3, and Ki-67, creating a scoring system based on these markers.
- Results indicated that the new risk score could independently predict patient survival, potentially offering a more personalized approach to treatment than classical methods.
Background: Esophagectomy carries a high risk of morbidity and mortality compared to other major surgeries. With the aim of creating an easy-to-use clinical preoperative risk assessment tool and to validate previously described risk factors for major complications following surgery, esophagectomies at two tertiary medical centers were analyzed.
Methods: A total of 450 patients who underwent esophagectomy for esophageal carcinoma at the University Medical Centre, Hamburg, or at the Medical Center University Duisburg-Essen, Germany (January 2008 to January 2020) were retrospectively analyzed.
Importance: Surgical site infections frequently occur after open abdominal surgery. Intraoperative wound irrigation as a preventive measure is a common practice worldwide, although evidence supporting this practice is lacking.
Objective: To evaluate the preventive effect of intraoperative wound irrigation with polyhexanide solution.
Metastasis is a cancer-related systemic disease and is responsible for the greatest mortality rate among cancer patients. Interestingly, the interaction between the immune system and cancer cells seems to play a key role in metastasis formation in the target organ. However, this complex network is only partially understood.
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