Publications by authors named "M Tabet"

Layer-specific brain computations depend on neurons synapsing with specific partners in distinct laminae. In the Drosophila lobula plate, axons of the four subtypes of T4 and T5 visual motion direction-selective neurons segregate into four layers, where they synapse with distinct subsets of postsynaptic neurons. Here, we identify a layer-specific expression of different receptor-ligand pairs of the Beat and Side families of cell adhesion molecules between T4/T5s and their postsynaptic partners.

View Article and Find Full Text PDF

Evidence from animal experiments has shown that chlorinated polyfluoroalkyl ether sulfonic acids (Cl-PFESAs) can induce vision dysfunction in zebrafish. However, environmental epidemiological evidence supporting this hypothesis remains limited. In our case-control study, samples collected from 270 individuals (135 controls and 135 cases) from the Isomers of C8 Health Project data were analyzed for Cl-PFESAs.

View Article and Find Full Text PDF
Article Synopsis
  • This study examined the relationship between a healthy lifestyle and cardiovascular diseases (CVDs) using data from over 161,000 participants in the UK Biobank.
  • Researchers created a metabolic signature based on 123 metabolites, which was inversely related to the risk of developing various CVDs over a 13-year follow-up period.
  • The findings suggest that improving metabolic health through lifestyle changes could help reduce the risk of CVD, indicating the potential for personalized prevention strategies.
View Article and Find Full Text PDF

Our study aimed to investigate the impact of tea and coffee consumption and related metabolomic signatures on dynamic transitions from diabetes-free status to incident type 2 diabetes (T2D), and subsequently to T2D-related complications and death. We included 438,970 participants in the UK Biobank who were free of diabetes and diabetes complications at baseline. Of these, 212,146 individuals had information on all metabolic biomarkers.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates how air pollution impacts chronic respiratory disease (CRD) risk by analyzing metabolomic data from over 171,000 participants without COPD or asthma.
  • Researchers found that higher exposure to particulate matter and nitrogen oxides correlated with increased CRD incidence, identifying specific metabolites linked to these pollutants.
  • The results suggest that certain metabolic processes, specifically inflammatory and erythrocyte-related pathways, mediate the effects of air pollution on CRD risk.
View Article and Find Full Text PDF