Publications by authors named "M T Warmerdam"
Emerging low-emission production technologies make ethanol an interesting substrate for yeast biotechnology, but information on growth rates and biomass yields of yeasts on ethanol is scarce. Strains of 52 Saccharomycotina yeasts were screened for growth on ethanol. The 21 fastest strains, among which representatives of the Phaffomycetales order were overrepresented, showed specific growth rates in ethanol-grown shake-flask cultures between 0.
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- The study investigates how the yeast C. jadinii grows on ethanol as a carbon source, looking specifically at growth rates, energy requirements, and biomass composition across different culture methods.
- In ethanol-limited conditions, C. jadinii CBS 621 achieves effective biomass yields and demonstrates a stable protein content, even at low growth rates, indicating its potential for producing single-cell protein.
- The research also finds that various C. jadinii strains grow rapidly on ethanol, and the results from chemostat cultures can help model production outcomes in larger fed-batch systems, highlighting differences in protein content due to cultivation conditions.
Article Synopsis
- Near-infrared fluorescence imaging in cancer surgery currently lacks a consistent method to assess the effectiveness of fluorescent dyes, leading to challenges in translating research findings from lab to clinical settings.
- The goal of this study is to create a semi-automatic method that provides an objective way to measure fluorescent signals in tissue samples post-surgery.
- The new method was tested and showed better consistency than traditional techniques, indicating it can enhance the reliability and standardization of studies involving fluorescent dyes in clinical applications.
Background: Fluorescence-guided surgery (FGS) has emerged as an innovative technique with promising applications in various surgical specialties. However, clinical implementation is hampered by limited availability of evidence-based reference work supporting the translation towards standard-of-care use in surgical practice. Therefore, we developed a consensus statement on current applications of FGS.
View Article and Find Full Text PDFColorectal polyps: Targets for fluorescence-guided endoscopy to detect high-grade dysplasia and T1 colorectal cancer.
United European Gastroenterol J
April 2023
Background: Differentiating high-grade dysplasia (HGD) and T1 colorectal cancer (T1CRC) from low-grade dysplasia (LGD) in colorectal polyps can be challenging. Incorrect recognition of HGD or T1CRC foci can lead to a need for additional treatment after local resection, which might not have been necessary if it was recognized correctly. Tumor-targeted fluorescence-guided endoscopy might help to improve recognition.
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