Mechanism of Action and Beneficial Effects of Probiotics in Amateur and Professional Athletes.

Probiotics are live microorganisms that, when administered in adequate amounts, provide health benefits to the host. According to the International Society of Sports Nutrition (ISSN), probiotic supplementation can optimize the health, performance, and recovery of athletes at all stages of their careers. Recent research suggests that probiotics can improve immune system functions, reduce gastrointestinal distress, and increase gut permeability in athletes.

A hybrid system of mixture models for the prediction of particle size and shape, density, and flowability of pharmaceutical powder blends.

This paper presents a system of hybrid models that combine both mechanistic and data-driven approaches to predict physical powder blend properties from their raw component properties. Mechanistic, probabilistic models were developed to predict the particle size and shape, represented by aspect ratio, distributions of pharmaceutical blends using those of the raw components. Additionally, the accuracy of existing mixture rules for predicting the blend's true density and bulk density was assessed.

Experimental solubility of omeprazole in pure and ethanol-modified subcritical water.

The current research aimed to study and measure the solubility of omeprazole (used to treat and reduce stomach acid) for the first time in pure subcritical and ethanol-modified water. These tests have been performed in the 25-130 °C temperature range and constant pressure of 20 bar with the use of 0-10% ethanol weight as the cosolvent. The solubility of omeprazole in subcritical water ranged from 0.

Free vibration optimization of 2D tri-axial braided composite fan blade with ANN-Anal-FEM-GA integrated model.

This research aimed to increase the natural frequencies of a non-rotating 2D tri-axial braided composite (2DTBC) fan blade. The investigation utilized a multidisciplinary approach, integrating Artificial Neural Network (ANN) modeling, analytical method, Finite Element (FE) analysis, optimization techniques, and experimental validation. The ANN captured the complex relationship between the braiding machine and structure parameters.

The impact of an open-label design on human amniotic membranes vs. silver sulfadiazine dressings for second-degree burns: a randomized controlled clinical trial.

Background: Burn wounds require optimal medical management due to associated psycho-emotional and socioeconomic impacts and severe pain. The use of synthetic and biological dressings improves healing and reduces burn wound complications. The present study aimed to compare the outcomes of using human amniotic membrane (hAM) dressings and conventional silver sulfadiazine (SSDZ) ointment dressings in the management of second-degree burn wounds.