[Primary generalized amyloidosis with restrictive cardiomyopathy and severe chronic cardiac insufficiency].

The paper reports a case of restrictive cardiomyopathy due to cardiac amyloidosis. Diagnosis of this condition encounters difficulty created by the absence of pathognomonic symptoms of the disease. Major manifestations of amyloid cardiomyopathy are refractive chronic cardiac insufficiency, absence of cardiomyalgia, marked deterioration of diastolic filling of both ventricles, systemic hypotension, and disturbed heart rhythms.

[Relationship of variability of blood pressure, cardiac sinus rhythm, and structural and functional characteristics of the left ventricular myocardium in elderly and senile patients with arterial hypertension].

The variability of blood pressure (BP), autonomic cardiac sinus rhythm regulation, and myocardial structural and functional characteristics of the left ventricle (LV) was comparatively analyzed in 201 patients aged 65-88 years who had uncomplicated systolic and diastolic and isolated systolic arterial hypertension (SDAH and ISAH, respectively). There was a greater variability of systolic and diastolic BP no matter what the type of arterial hypertension (AH) was. It was ascertained that ISAH was characterized by absolute parasympaticotonia and SDAH was marked by relative sympaticotonia with the involvement of central ergotropic and humoral-and-metabolic mechanisms.