Publications by authors named "M T Pardi"
Article Synopsis
- Subaortic stenosis (SubAS) can remain undiagnosed until pregnancy, where the hemodynamic changes may reveal severe symptoms, necessitating urgent treatment.
- A case study presents a 34-year-old pregnant woman who underwent surgery after being admitted for severe SubAS, successfully delivering a healthy baby at 39 weeks post-surgery.
- Managing heart conditions like SubAS during pregnancy poses risks, but with careful planning and teamwork among healthcare providers, successful outcomes can be achieved.
Background: The aim of this study was to determine if there is a correlation between fluoride release, surface hardness, and diametral tensile strength of restorative glass ionomer cements (GICs).
Material And Methods: Conventional (Riva Self Cure) and resin-modified (Riva Light Cure) GICs were used. Thirty-four samples (ø 6 x 3 mm) were prepared for each cement.
Article Synopsis
- Circular RNAs (circRNAs) are noncoding RNAs, and many have unknown biological functions due to challenges in studying them.
- This study specifically investigated circTulp4, a circRNA found in the brain, by creating a mouse model that lacks circTulp4 while preserving normal mRNA and protein levels.
- The findings show that circTulp4 is essential for proper brain function, influencing neurotransmission and responses to negative stimuli, highlighting the importance of circRNAs in neural regulation.
Background: Community acquired pneumonia (CAP) is the most frequent cause of mortality secondary to infectious etiologies. Recommendations about the use of blood cultures in the diagnosis and treatment of CAP has been a contentious topic of debate and ever-changing recommendations.
Methods: A cohort study was conducted in a community teaching hospital.
Top-down projections convey a family of signals encoding previous experiences and current aims to the sensory neocortex, where they converge with external bottom-up information to enable perception and memory. Whereas top-down control has been attributed to excitatory pathways, the existence, connectivity, and information content of inhibitory top-down projections remain elusive. Here, we combine synaptic two-photon calcium imaging, circuit mapping, cortex-dependent learning, and chemogenetics in mice to identify GABAergic afferents from the subthalamic zona incerta as a major source of top-down input to the neocortex.
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