Publications by authors named "M T P Odenthal"

Article Synopsis
  • Fuchs endothelial corneal dystrophy (FECD) is a genetic and age-related disease leading to the loss of corneal endothelial cells, resulting in corneal swelling and vision issues.
  • Advanced FECD often shows a fibrillar layer (FL) on the corneal surface, especially in the inferotemporal quadrant, which can be measured using specialized imaging techniques.
  • Current treatments mainly involve corneal transplantation, particularly DMEK surgery, with new approaches like smaller grafts and advancements in imaging for better assessment and planning of surgeries.
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Small cell lung cancer (SCLC) is the most aggressive lung cancer entity with an extremely limited therapeutic outcome. Most patients are diagnosed at an extensive stage. However, the molecular mechanisms driving SCLC invasion and metastasis remain largely elusive.

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Background: Obesity and nonalcoholic fatty liver disease (NAFLD) are an increasing health care burden worldwide. Weight loss is currently the best option to alleviate NAFLD and is efficiently achieved by bariatric surgery. Presence of NAFLD seems to be predictive for postoperative weight loss.

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Preterm infants with oxygen supplementation are at high risk for bronchopulmonary dysplasia (BPD), a neonatal chronic lung disease. Inflammation with macrophage activation is central to the pathogenesis of BPD. CXCL10, a chemotactic and pro-inflammatory chemokine, is elevated in the lungs of infants evolving BPD and in hyperoxia-based BPD in mice.

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