Assessment of cardiac function by echocardiography in Paget's disease of bone.

Objective: To identify the mechanisms which influence the development of cardiac insufficiency in Paget's disease of bone (PD).

Methods: In this hospital-based case-control study 23 consecutive, recently diagnosed and untreated PD patients were compared against 23 controls frequency-matched by sex, age and body index. All subjects underwent non-invasive assessment of cardiac function by two-dimensional Doppler echocardiography.