Publications by authors named "M T Mugnaini"

Gamma oscillations are disrupted in various neurological disorders, including Alzheimer's disease (AD). In AD mouse models, non-invasive audiovisual stimulation (AuViS) at 40 Hz enhances gamma oscillations, clears amyloid-beta, and improves cognition. We investigated mechanisms of circuit remodeling underlying these restorative effects by leveraging the sensitivity of hippocampal neurogenesis to activity in middle-aged wild-type mice.

View Article and Find Full Text PDF
Article Synopsis
  • The study examines the effectiveness of two spacer types used during two-stage exchange arthroplasty for chronic prosthetic joint infections in the hip, focusing on mechanical complications and bone preservation.
  • A retrospective review of 40 patients revealed that Articulating Spacers with acetabular cement had lower dislocation rates and better preservation of acetabular bone compared to Hemi-Spacers.
  • The results indicate that using dynamic spacers with cement augmentation contributes to improved surgical outcomes, including quicker recovery during the second stage of surgery.
View Article and Find Full Text PDF

Introduction: The optimal treatment approach for Bony Bankart remains a subject of considerable debate among shoulder surgeons. Existing literature highlights low recurrence rates and high patient satisfaction with nonoperative treatment, particularly in the middle-aged population. This study aimed to evaluate the recurrence rate of dislocation, as well as the clinical and functional outcomes in middle-aged individuals treated nonoperatively following an acute bony Bankart fracture.

View Article and Find Full Text PDF
Article Synopsis
  • * Clot permeability is a key factor influencing clot structure and resistance to breakdown, highlighting the need for standardized measurement techniques to assess this parameter accurately.
  • * The study introduces a portable and cost-effective system for measuring blood clot permeability using a pressure-based method, demonstrating significant differences in permeability between high cardiovascular-risk patients and controls, which could enhance thrombotic risk assessment in clinical settings.
View Article and Find Full Text PDF

Quartz Crystal Microbalances (QCMs) are versatile sensors employed in various fields, from environmental monitoring to biomedical applications, owing mainly to their very high sensitivity. However, the assessment of their metrological performance, including the impact of conditioning circuits, digital processing algorithms, and working conditions, is a complex and novel area of study. The purpose of this work is to investigate and understand the measurement errors associated with different QCM measurement techniques, specifically focusing on the influence of conditioning electronic circuits.

View Article and Find Full Text PDF