Publications by authors named "M T Madison"

Background: TransCarotid artery revascularization (TCAR) is a safe minimally invasive option for patients with carotid artery stenosis who are not appropriate candidates for carotid endarterectomy (CEA). Many physicians have not yet adopted this technique in the management of carotid artery stenosis. The aim of this study is to explore overall outcomes of carotid revascularization based on physicians' practices in the Vascular Quality Initiative (VQI).

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Objective: Prior studies have emphasized the importance of compliance with preoperative dual antiplatelet therapy (DAPT) in patients undergoing TransCarotid artery revascularization (TCAR). This investigation examines differences in perioperative outcomes following TCAR in those receiving loading dose of antiplatelet medications on the day of the procedure versus those already maintained on DAPT.

Methods: Consecutive TCAR procedures from the Vascular Quality Initiative (2016-2022) were identified.

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Article Synopsis
  • - Peripheral arterial disease (PAD) impacts over 8.5 million Americans and is the top cause of amputations in the U.S., yet there is low awareness among patients and healthcare providers about the condition, highlighting a need for better identification methods.
  • - Traditional identification methods, such as keyword search (KWS), are limited by their rigidity and inability to effectively capture undiagnosed PAD cases, making them less effective for varied clinical data.
  • - The study explores the use of deep learning (DL) in natural language processing (NLP) to potentially improve the identification of PAD patients through analysis of unstructured clinical notes in electronic health records (EHR), providing a more flexible and accurate approach than KWS.
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Article Synopsis
  • * In the experiment, diabetic mice underwent surgery to induce CLTI, followed by vBA-MSC injections into the affected muscle, which resulted in improved limb perfusion, muscle recovery, and reduced fibrosis when compared to control mice.
  • * Results showed significant upregulation of key genes associated with muscle regeneration and angiogenesis, suggesting that vBA-MSC therapy offers a promising approach to enhance recovery in ischemic muscle conditions.
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