The shifting gender composition of psychology. Trends and implications for the discipline.

Psychology, along with the majority of professions and scientific disciplines, has undergone dramatic shifts in gender composition over the past two decades. These changes have prompted concern that this increased participation by women may lead to erosion in the status of these occupations. This article describes the results of a case study of psychology conducted by a subcommittee of the American Psychological Association's (APA's) Task Force on the Changing Gender Composition of Psychology to examine the discipline's changing gender composition and the factors related to these shifts.

A hydrophobic binding site in acetylcholinesterase.

The dissociation constants have been determined and compared for a series of reversible, noncovalent inhibitors of eel acetylcholinesterase that are structurally related to the very potent inhibitor, 1,2,3,4-tetrahydro-9-aminoacridine (THA). It is concluded that there exists on the enzyme protein, closely adjacent to the anionic subsite, a conformationally flexible, hydrophobic area which tends readily to assume a near planar form. The dimensions of this area are unknown, but it is adequate in size to fully accomodate THA.