Does access to free medication reduce health system costs? An evaluation of the Dispensary of Hope program.

Cost-related medication nonadherence-when patients fail to take medication as prescribed because of the cost of the medication-has numerous consequences: more hospitalizations, avoidable deaths, and greater health care expenditures. Dispensary of Hope is a charitable medication access program that collects and distributes pharmaceuticals to pharmacies to dispense free of charge to patients with no insurance, low incomes, and chronic conditions. To estimate the differences in medical costs and utilization of hospital patients enrolled in the Dispensary of Hope program relative to those who were not enrolled.

Comprehensive Characterization of Cerebrovascular Dysfunction in Blast Traumatic Brain Injury Using Photoacoustic Microscopy.

Blast traumatic brain injury (bTBI) is a leading contributor to combat-related injuries and death. Although substantial emphasis has been placed on blast-induced neuronal and axonal injuries, co-existing dysfunctions in the cerebral vasculature, particularly the microvasculature, remain poorly understood. Here, we studied blast-induced cerebrovascular dysfunctions in a rat model of bTBI (blast overpressure: 187.

Polarization-based control of spin-orbit vector modes of light in biphoton interference.

We report the experimental generation of a class of spin-orbit vector modes of light via an asymmetric Mach-Zehnder interferometer, obtained from an input beam prepared in a product state of its spin and orbital degrees of freedom. These modes contain a spatially varying polarization structure which may be controllably propagated about the beam axis by varying the retardance between the vertical and horizontal polarization components of the light. Additionally, their transverse spatial intensity distributions may be continuously manipulated by tuning the input polarization parameters.

Prescribing Preferences in the First-Line Treatment for Patients With Metastatic Renal Cell Carcinoma in the United States.

Background: Despite existing guidelines for first-line treatment of metastatic renal cell carcinoma (mRCC), prescribing preferences in the United States have not been fully examined. The objectives of this study were to characterize US physicians' preferences and factors influencing first-line mRCC treatment.

Materials And Methods: A Web-based study presented physicians with hypothetical mRCC patient cases and recorded initial therapy preference and rationale.